Organisation : Medical Services Recruitment Board (MRB)
Post Name : MRB Pharmacist Recruitment 2022
Qualification : Diploma in Pharmacy or Bachelor of Pharmacy or Pharm. D
Announcement : MRB Pharmacist Exam Syllabus
Website : https://www.mrb.tn.gov.in/notifications.html
What is MRB Pharmacist Recruitment?
MRB Pharmacist Recruitment is organised by Medical Services Recruitment Board. Applications are invited only through online mode up to 30.08.2022 for direct recruitment on temporary basis to the post of Pharmacist in Tamil Nadu Medical Subordinate Service. A Diploma in Pharmacy or Bachelor of Pharmacy or Pharm. D. Must have registered with Tamil Nadu Pharmacy Council and must keep the registration alive by renewing it regularly every year. The Last Date of submission is 30th August, 2022.
Syllabus For MRB Pharmacist Exam
The Syllabus For MRB Pharmacist Exam are given below,
(1) Pharmaceutics:
Definition, types, theoretical and practical aspects, methods of preparation/formulation, vehicles, adjuvants and excipients used, quality control, containers and closures, special labelling requirements and storage conditions etc. of (a) Solid dosage forms – powders, granules, cachets and tablet triturates, tablets and capsules. (b) Liquid dosage forms: mixtures, syrups, elixirs, gargles, mouthwashes, throat paints, douches, ear drops, nasal drops, sprays, liniments, lotions, suspensions and emulsions (c) Semi-solid dosage forms – ointments,
pastes, jellies, poultices, suppositories and pessaries. (d) Dental and Cosmetic Preparation – dentrifices, facial cosmetics, deodorants, antiperspirants, shampoos, hair dressing and hair removers. (e) Sterile Dosage Forms: (i) Parenteral dosage forms – preparation of Intravenous fluids and admixtures – Total parenteral nutrition, – Dialysis fluids – Sterility testing – Particulate matter monitoring – Faulty seal packaging and (ii) Ophthalmic Products – study of essential characteristics of different ophthalmic preparations – formulation additives, special precautions in handling and storage of ophthalmic products. Study of immunological products like sera vaccines, toxoids & their preparations. and introduction to Ayurvedic dosage forms.
Prescriptions – Latin terms commonly used in prescriptions- Modern methods of prescribing, adoption of metric system. Calculations involved in dispensing – Incompatibilities in Prescriptions – Study of various types of incompatibilities – Posology – dose and Dosage of drugs – factors influencing dose – calculations of doses on the basis of age, sex and surface area – veterinary doses. Systems of weights and measures – calculations including conversion from one to another system. Percentage calculations and adjustments of products. Use of
alligation method in calculations, Isotonic solutions. Introduction to Pharmacopoeias
with special reference to the Indian Pharmacopoeia. Definition, theory, objectives, types, factors influencing, advantages and disadvantages, uses and equipments for the following processes: (a) Size reduction, (b) Size separation (c) Mixing and homogenisation, (d) Clarification and filtration (e) Extraction (f) Distillation (g) Drying (h) Sterilization (i) Aseptic techniques etc.
(2) Pharmaceutical Chemistry:
General discussion on the following inorganic compounds including important physical and chemical properties, medicinal and pharmaceutical uses, storage conditions and chemical incompatibility belonging to to following categories:
(A) Acids, bases and buffers (B) Antioxidants (C) Gastrointestinal agents including acidifying agents, antacids, protectives and saline cathartics (D) Topical Agents including protectives,
antimicrobials and astringents (E) Dental Products (F) Inhalants (G) Respiratory stimulants (H) Expectorants and Emetics and (I) Antidotes-Sodium nitrate.
Major Intra and Extracellular electrolytes: (A) Electrolytes used for replacement therapy (B) Physiological acid-base balance and electrolytes (C) Combination of
oral electrolyte powders and solutions.
Radio pharmaceuticals and Contrast media: Radio activity-Alpha, Beta and
Gamma Radiations, Biological effects of radiations, Measurement of radio activity, G. M. Counter Radio isotopes their uses, storage and precautions with special reference to the official preparations. Quality control of Drugs and Pharmaceuticals -Importance of quality control, significant errors, methods used for quality control, sources of impurities in Pharmaceuticals, Limit tests for Arsenic, chloride, sulphate, Iron and Heavy metals and Identification tests for cations and anions as per Indian Pharmacopoeia. Chemistry of following pharmaceutical organic compounds, covering their nomenclature, chemical structure, uses and the important physical and chemical properties, stability and storage conditions and the different type of pharmaceutical formulations of these drugs and their popular brand names of
drugs belonging to:
(a) Antiseptics and disinfectants (b) Sulfonamides (c) Antileprotic drugs (d) Anti- tubercular drugs (e) Antiamoebic and Anthelmintic drugs (f) Antibiotics – Penicillins Gentamicin, Neomycin , Erythromycin , Tetracyclines, Cephalosporins exin, Cephaloridine , Cephalothin, Griseofulvin , Chloramphenicol. (g) Antifungal agents (h) Antimalarial Drugs. (i) Tranquilizers (j) Sedatives and Hypnotics (k) General and Local Anaesthetics (l) Antidepressant drugs (m) Analeptics (n) Adrenergic and Adrenergic Antagonist drugs (o) Cholinergic and Anti-cholinergic Drugs (p) Diuretics (q) Cardiovascular Drugs (r) Hypoglycemic Agents (s) Coagulants and Anti- Coagulants (t) Histamine and Anti-histaminic Agents (u) Analgesics and Anti-pyretics
(v) Non-steroidal anti-inflammatory Agents (w) Diagnostic Agents (x) Anticonvulsants (y) Cardiac glycosides (z) Antiarrhythmic agents (aa) Antihypertensives (ab) Vitamins. (ac) Steroidal Drugs (ad) Anti-Neoplastic drugs.
(3) Pharmacognosy:
Definition, history and scope of Pharmacognosy including indigenous system of medicine – various systems of classification of drugs of natural origin – adulteration and drug evaluation – significance of pharmacopoeial standards. Brief outline of occurrence, distribution, outline of isolation, identification tests, therapeutic effects and pharmaceutical applications of alkaloids, terpenoids, glycosides, volatile oils, tannins and resins Occurrence, distribution, organoleptic evaluation, chemical constituents including identification tests, pharmaceutical applications of following categories of drugs
(a) Laxatives: Aloes, Rhuburb, Castor oil, Ispaghula, Senna.
(b) Cardiotonics: Digitalis, Arjuna.(c) Carminatives & G.I. regulators: Umbelliferous fruits, Coriander, Fennel, Ajowan, Cardamom Ginger, Black pepper, Asafoetida, Nutmeg, Cinnamon, Clove. (d) Astringents – Catechu. (e) Drugs acting on nervous system- Hyoscyamus, Belladonna, Aconite, Ashwagandha, Ephedra, Opium, Cannabis, Nux vomica. (f) Antihypertensives – Rauwolfia. (g) Antitussives – Vasaka, Tolu balsam, Tulsi. (h) Antirheumatics – Guggul, Colchicum. (i) Antitumour – Vinca.
(j) Antileprotics – Chaulmoogra Oil. (k) Antidiabetics -Pterocarpus, Gymnema, Sylvestro. (l) Diuretics – Gokhru, Punarrnava. (m) Antidysentrics – Ipecacuanha
(n) Antiseptics and disinfectants – Benzoin, Myrrh. Nim, curcuma. (o) Antimalarials – Cinchona. (p) Oxytocics – Ergot. (q) Vitamines – Shark liver Oil and Amla.
(r) Enzymes – Papaya, Diastase, Yeast. (s) Perfumes and flavouring agents – Peppermint Oil, Lemon Oil, Orange Oil, Lemon grass Oil, Sandalwood.
(t) Pharmaceutical aids – Honey, Arachis Oil, Starch, Kaolin, Pectin, Olive oil, Lanolin, Beeswax, Acacia, Tragacanth, Sodium alginate, Agar, Guar gum, Gelatin.
(u) Miscellaneous – Liquorice, Garlic, Picrorhiza, Dioscorea, Linseed, Shatavari, Shankhapusphi, Pyrethrum, Tobacco. (v) fibres used in sutures and surgical dressings – cotton, silk, wool and regenerated fibre.
(4) Pharmacology & Toxicology:
Introduction and scope of Pharmacology. Routes of administration, absorption, metabolism, distribution and excretion of drugs. Bio-availability and mechanism of drugs action and the factors modifying drug action Pharmacological classification, mechanism of action, chemistry, adverse effects, uses and dosage of drugs acting on Central Nervous System namely general anaesthetics, local anaesthetics, analgesics, antipyretics and non-steroidal anti-inflammatory drugs, narcotic analgesics, antirheumatics and anti gout remedies, sedatives and hypnotics,
psychopharmacological agents, anti convulsants and analeptics, centrally acting muscle relaxants and anti parkinsonism agents.
Autonomic nervous system: Cholinergic and anticholinergic drugs, anti cholinesterase drugs, adrenergic and adrenergic receptor blockers, neurone blockers and ganglion blockers, neuromuscular blockers, drugs used in myasthenia gravis.
Respiratory system: Respiratory stimulants, bronchodilators, nasal decongestants, expectorants and Antitussive agents.
Cardio Vascular System: Cardiotonics, antiarrhythmic agents, antianginal agents, antihypertensive agents, peripheral vasodilators and drugs used in atherosclerosis. haematinics, coagulants and anticoagulants, haemostatics, blood substitutes and plasma expanders.
Digestive system: Carminatives, digestants bitters, antacids and drugs used in peptic ulcer, purgatives, and laxatives, antidiarrhoeals, emetics and antiemetics, anti- spasmodics.
Miscellaneous: Diuretics and antidiuretics, histamine and antihistamines, prostaglandins. Hypoglycemic agents, antithyroid drugs, sex hormones and oral contraceptives, corticosteroids.
Chemotherapy of microbial disease: Urinary antiseptics, Sulphonamides, Penicillins, Streptomycin, Tetracylines and other antibiotics, Antitubercular agents, Antifungal agents, antiviral drugs, antileprotic drugs. Chemotherapy of protozoal diseases, Anthelmintic drugs. Chemotherapy of cancer. Disinfectants and antiseptics.
Syllabus : http://www.syllabus.gen.in/uploads/pdf2022/2823-syllabus.pdf
(5) Drug Store & Business Management:
Commerce: Introduction – Trade, Industry and Commerce – functions and subdivision of commerce – introduction of elements of Economics and Management – Forms of Business
Organisations – Banking and Finance Service – functions of the bank – finance planning – sources of finance. Channels of Distribution – Drug House Management – Selection of Site, Space Lay- out and legal requirements – Purchasing – selection of suppliers, credit information,
tenders, contracts and price determination and legal requirements thereto.