GATE Biotechnology (BT) Syllabus 2023
Organisation : Graduate Aptitude Test In Engineering GATE
Exam Name : Biotechnology (BT) Exam
Announcement : GATE Biotechnology (BT) Syllabus 2023
Website : https://gate.iitk.ac.in
GATE Biotechnology (BT) Syllabus
In each of the following subjects the topics have been divided into two categories – Core Topics and Special Topics. The corresponding sections of the question paper will contain 90% of their questions on Core Topics and the remaining 10% on Special Topics.
Related / Similar Syllabus : GATE Biomedical Engineering (BM) Syllabus 2023
Biotechnology (BT) Syllabus
Section 1: Engineering Mathematics
Linear Algebra:
Matrices and determinants; Systems of linear equations; Eigen values and Eigen vectors. Calculus: Limits, continuity and differentiability; Partial derivatives, maxima and minima; Sequences and series; Test for convergence.
Differential Equations:
Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients; Cauchy’s and Euler’s equations; Laplace transforms. Probability and Statistics: Mean, median, mode and standard deviation; Random variables; Poisson, normal and binomial distributions; Correlation and regression analysis.
Numerical Methods:
Solution of linear and nonlinear algebraic equations; Integration by trapezoidal and Simpson’s rule; Single step method for differential equations.
Section 2: General Biology
Biochemistry:
Biomolecules – structure and function; Biological membranes – structure,membrane channels and pumps, molecular motors, action potential and transport processes; Basic concepts and regulation of metabolism of carbohydrates, lipids, amino acids and nucleic acids; Photosynthesis, respiration and electron transport chain. Enzymes – Classification, catalytic and regulatory strategies; Enzyme kinetics – Michaelis-Menten equation; Enzyme inhibition – competitive, non-competitive and uncompetitive inhibition.
Microbiology:
Bacterial classification and diversity; Microbial Ecology – microbes in marine, freshwaterand terrestrial ecosystems; Microbial interactions; Viruses – structure and classification; Methods in microbiology; Microbial growth and nutrition; Nitrogen fixation; Microbial diseases and host-pathogen interactions; Antibiotics and antimicrobial resistance.
Immunology:
Innate and adaptive immunity, humoral and cell mediated immunity; Antibody structure and function; Molecular basis of antibody diversity; T cell and B cell development; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organs; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation ofimmune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus hostreaction; Immunization and vaccines.
Section 3: Genetics, Cellular and Molecular Biology
Genetics and Evolutionary Biology:
Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics – transformation, transduction and conjugation; Horizontal gene transfer and transposable elements; Chromosomal variation; Genetic disorders; Population genetics; Epigenetics; Selection and inheritance; Adaptive and neutral evolution; Genetic drift; Species and speciation.
Cell Biology:
Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-cell communication; Cell signalling and signaltransduction; Post-translational modifications; Protein trafficking; Cell death and autophagy; Extra-cellular matrix.
Molecular Biology:
Molecular structure of genes and chromosomes; Mutations and mutagenesis; Regulation of gene expression; Nucleic acid – replication, transcription, splicing, translation and their regulatory mechanisms; Non-coding and micro RNA; RNA interference; DNA damage and repair.
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